Pyrimido[1,2-a]-purin-10(3H)-one, M1G, is less prone to artifact than base oxidation
نویسندگان
چکیده
منابع مشابه
Pyrimido[1,2-a]-purin-10(3H)-one, M1G, is less prone to artifact than base oxidation
Pyrimido[1,2-a]-purin-10(3H)-one (M1G) is a secondary DNA damage product arising from primary reactive oxygen species (ROS) damage to membrane lipids or deoxyribose. The present study investigated conditions that might lead to artifactual formation or loss of M1G during DNA isolation. The addition of antioxidants, DNA isolation at low temperature or non-phenol extraction methods had no statisti...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2005
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gki944